The TBPod

The TBPod is a podcast for clinicians and policymakers caring for patients with tuberculosis. The podcasts present discussions with expert clinicians, researchers, policymakers and advocates about their work in the field of tuberculosis. Tuberculosis remains one of the leading causes of death worldwide, and is an important contributor to morbidity among migrants arriving in Australia and New Zealand. There are around 1300 reported cases of TB in Australia each year, and a further 300 in New Zealand. Included in these figures are cases of multi-drug resistant (MDR) TB which pose significant barriers to treatment and management of the disease. The Australian government has committed to the global elimination of TB by 2030, but to do so requires the development of innovative new strategies, based on high-quality research, that has national and international reach. These podcasts aim to engage and update those who are interested in the field of tuberculosis through discussions with leaders in the field of tuberculosis.

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The TBPod

Differentiating TB from Sarcoid

July 01, 2023 • Actnet

Today we have the pleasure of speaking to both Professor Leonard (Respiratory physician and director of the sarcoidosis service for Manchester Foundation Trust) and Dr Montero (director of cellular pathology for Wythenshawe Hospital) about the complex interplay between these two illnesses and how best to approach complex patients with uncertain diagnosis of granulomatous disease.

REFERENCES:
Agrawal, Rupesh, et al. "Tuberculosis or sarcoidosis: opposite ends of the same disease spectrum?." Tuberculosis 98 (2016): 21-26.

Baughman, Robert P., et al. "ERS clinical practice guidelines on treatment of sarcoidosis." European respiratory journal58.6 (2021).

Fang, Chuling, Hui Huang, and Zuojun Xu. "Immunological evidence for the role of mycobacteria in sarcoidosis: a meta-analysis." PLoS One 11.8 (2016): e0154716.

Malkova, Anna, et al. "The opposite effect of human leukocyte antigen genotypes in sarcoidosis and tuberculosis: A narrative review of the literature." ERJ Open Research 6.3 (2020).

Mortaz, Esmaeil, Ian M. Adcock, and Peter J. Barnes. "Sarcoidosis: Role of non-tuberculosis mycobacteria and Mycobacterium tuberculosis." International journal of mycobacteriology 3.4 (2014): 225-229.